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Track listing "Love Theme" "Angel" "I Love You" "It's My Life" "Hey Baby" "Why Can't This Be Love" "Bathwater" "Sunday Morning" References Category:Paula Abdul albums Category:1999 albums Category:Contemporary R&B albums by American artists Category:Dance-pop albums by American artistsMoisture-induced matrix stiffening in aqueous solutions containing misfolded proteins. The force spectroscopy of water in contact with biomolecules is an emerging research area with a variety of interesting and useful applications in biology and medicine. Here we report a systematic study of the impact of protein misfolding on the strength of water-protein interactions, as a function of the solution concentration and the position of the protein conformation on the free-energy landscape. Using atomic force microscopy, we found that water condensation is less effective in stiffening protein-water networks in solutions that also contain misfolded proteins. Additionally, our data show that the same phenomenon is seen in both the native and the misfolded protein state. These findings are consistent with our current understanding of the relationship between the structure of protein and water and support the view that hydration of proteins involves the formation of a water-structured environment in which water-protein interactions are less efficient than in the native state.Q: Probability, likelihood and Bayes In the probability book of Allen Guttmacher, the author writes: A probability distribution is called the likelihood of the observation if it is the conditional probability distribution of $X$ given $Y$ While in the Bayes theorem the conditional probability is written as: where $P(A|B)$ is the conditional probability that $A$ is true given that $B$ is true I have to admit that I don't really understand how to differentiate the definitions. For instance, given the image above, It is obvious to me that the likelihood is $P(X|Y)$ (or $P(Y|X)$), which is defined as the ratio between the probability of the event $X$ if the event $Y$ occurs and the probability of the event $Y$ if the event $X$ occurs. Similarly, the likelihood is the probability of the event $X$ given

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